Progressive Multiple Sclerosis Transcriptome Deconvolution Indicates Increased M2 Macrophages in Inactive Lesions
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DOI: 10.1159/000510075
Abstract: Accumulating evidence suggests M2 macrophages contribute to tissue reparation and limit inflammation in multiple sclerosis (MS). However, most studies have focused on murine models without substantial support through human MS observations. The present study aimed… read more here.
Keywords: progressive multiple; inactive lesions; multiple sclerosis; deconvolution ... See more keywords
Demyelinating lesions and progressive MS
Sign Up to like & getrecommendations! Published in 2019 at "Neurology"
DOI: 10.1212/wnl.0000000000007933
Abstract: In multiple sclerosis (MS), the majority of patients experience neurologic relapses followed by recovery and later—on average 10 to 15 years after onset in adult patients1,2 and 20 years after onset in pediatric patients3—develop progressive… read more here.
Keywords: lesions progressive; injury; demyelinating lesions;