Downregulation of lncRNA ANRIL represses tumorigenicity and enhances cisplatin‐induced cytotoxicity via regulating microRNA let‐7a in nasopharyngeal carcinoma
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.21904
Abstract: Many studies have demonstrated that upregulation of long non‐coding RNA (lncRNA) antisense non‐coding RNA in the INK4 locus (ANRIL) plays an oncogenic role in various tumors, including nasopharyngeal carcinoma (NPC). The aim of this study… read more here.
Keywords: anril; anril represses; induced cytotoxicity; let ... See more keywords
Atherosclerosis‐associated endothelial cell apoptosis by miRNA let7‐b‐mediated downregulation of HAS‐2
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.29537
Abstract: MicroRNAs (miRNAs) play essential roles in the regulation and pathophysiology of various types of human diseases including atherosclerosis. Increasing numbers of miRNAs have been identified to be important regulators in the progression of atherosclerosis by… read more here.
Keywords: apoptosis; associated endothelial; endothelial cell; atherosclerosis associated ... See more keywords
A functional variant in the flanking region of pri‐let‐7f contributes to colorectal cancer risk in a Chinese population
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.28227
Abstract: Let‐7f was reported to be downregulated in patients with colorectal cancer (CRC). However, little is known about the role of let‐7f in CRC carcinogenesis. The aim of this study was to investigate the correlation between… read more here.
Keywords: risk; colorectal cancer; pri let; crc ... See more keywords
IL‐1β/NF‐κB signaling inhibits IGF‐1 production via let‐7f‐5p in dendritic epidermal T cells
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Leukocyte Biology"
DOI: 10.1002/jlb.3ma0322-171r
Abstract: Dendritic epidermal T cells (DETCs) are the main source of insulin‐like growth factor‐1 (IGF‐1) in epidermal tissue, which promote re‐epithelialization and wound healing. In refractory wounds, IL‐1β has been shown to activate NF‐κB and suppress… read more here.
Keywords: epidermal cells; wound healing; dendritic epidermal; let ... See more keywords
Spatial fractionation of the dose in heavy ions therapy: An optimization study
Sign Up to like & getrecommendations! Published in 2018 at "Medical Physics"
DOI: 10.1002/mp.12902
Abstract: PURPOSE The alliance of charged particle therapy and the spatial fractionation of the dose, as in minibeam or Grid therapy, is an innovative strategy to improve the therapeutic index in the treatment of radioresistant tumors.… read more here.
Keywords: heavy ions; fractionation dose; spatial fractionation; ratio ... See more keywords
Dose‐ rather than fluence‐averaged LET should be used as a single‐parameter descriptor of proton beam quality for radiochromic film dosimetry
Sign Up to like & getrecommendations! Published in 2020 at "Medical Physics"
DOI: 10.1002/mp.14097
Abstract: Purpose The dose response of Gafchromic EBT3 films exposed to proton beams depends on the dose, and additionally on the beam quality, which is often quantified with the linear energy transfer (LET) and, hence, also… read more here.
Keywords: averaged let; proton; fluence averaged; film ... See more keywords
Technical note: In silico benchmarking of the linear energy transfer-based functionalities for carbon ion beams in a commercial treatment planning system.
Sign Up to like & getrecommendations! Published in 2022 at "Medical physics"
DOI: 10.1002/mp.16174
Abstract: BACKGROUND The increasing number of studies dealing with linear energy transfer (LET)-based evaluation and optimization in the field of carbon ion radiotherapy (CIRT) indicates the rising demand for LET implementation in commercial treatment planning systems… read more here.
Keywords: carbon ion; let; linear energy; treatment ... See more keywords
Processing-Challenges Generated by Clusters of DNA Double-Strand Breaks Underpin Increased Effectiveness of High-LET Radiation and Chromothripsis.
Sign Up to like & getrecommendations! Published in 2018 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-981-13-0593-1_10
Abstract: Whereas most endogenous and exogenous DNA damaging agents typically generate lesions that are relatively isolated and can be repaired easily, ionizing radiation (IR) also induces clustered lesions causing DNA double strand breaks (DSBs). Moreover, forms… read more here.
Keywords: dsb clusters; processing; chromothripsis; high let ... See more keywords
The effect of lateral extra-articular tenodesis on in vivo cartilage contact in combined anterior cruciate ligament reconstruction
Sign Up to like & getrecommendations! Published in 2021 at "Knee Surgery, Sports Traumatology, Arthroscopy"
DOI: 10.1007/s00167-021-06480-4
Abstract: Lateral extra-articular tenodesis (LET) may confer improved rotational stability after anterior cruciate ligament reconstruction (ACLR). Little is known about how LET affects in vivo cartilage contact after ACLR. The aim of this study was to… read more here.
Keywords: effect; vivo cartilage; let; cartilage contact ... See more keywords
Rational versus transcendental points on analytic Riemann surfaces
Sign Up to like & getrecommendations! Published in 2021 at "manuscripta mathematica"
DOI: 10.1007/s00229-021-01324-4
Abstract: Let (X, L) be a polarized variety over a number field K. We suppose that L is an hermitian line bundle. Let M be a non compact Riemann Surface and $$U\subset M$$ be a relatively compact… read more here.
Keywords: bounded polynomial; varphi; let; versus transcendental ... See more keywords
MicroRNA let-7c Improves LPS-Induced Outcomes of Endometritis by Suppressing NF-κB Signaling
Sign Up to like & getrecommendations! Published in 2018 at "Inflammation"
DOI: 10.1007/s10753-018-0922-4
Abstract: Endometritis is a common inflammatory disease which endangers human and animal reproductive health. MicroRNA (miRNA) let-7c plays an important role in the inflammatory process; however, the regulatory underlying mechanism of let-7c in endometritis is unclear.… read more here.
Keywords: lps induced; let improves; microrna let; let ... See more keywords