TAKOTSUBO CARDIOMYOPATHY (TCM) INCREASES RISK OF LETHAL ARRHYTHMIAS
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DOI: 10.1016/s0735-1097(17)34238-9
Abstract: Background: Takotsubo cardiomyopathy (TCM), although generally considered reversible, can be associated with significant mortality due to lethal arrhythmias. Repolarization abnormalities in TCM can lead to characteristic T-wave abnormalities & QT prolongation that place patients at… read more here.
Keywords: lethal arrhythmias; takotsubo cardiomyopathy; tcm increases; increases risk ... See more keywords
4968Increased Gao expression underlies cardiac dysfunction and lethal arrhythmias accompanied with abnormal Ca2+ handling
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DOI: 10.1093/eurheartj/ehz746.0027
Abstract: We previously demonstrated that a transcriptional repressor, neuron restrictive silencer factor (NRSF), maintains normal cardiac function and electrical stability. Transgenic mice expressing a dominant-negative mutant of NRSF in their hearts (dnNRSF-Tg) exhibit systolic dysfunction with… read more here.
Keywords: dysfunction; ca2 handling; lethal arrhythmias; expression ... See more keywords
P5975Diminished LV systolic velocity on tissue Doppler imaging is linked to an amplified risk of lethal arrhythmias independently of LV ejection fraction
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DOI: 10.1093/eurheartj/ehz746.0696
Abstract: Life threatening arrhythmias (LTA) can trigger sudden cardiac death, or provoke implantable cardioverter defibrillator (ICD) discharges that escalate morbidity and mortality. Longitudinal myofibrils predominate in the subendocardium which is uniquely sensitive to arrhythmogenic triggers. To… read more here.
Keywords: systolic velocity; risk; velocity tissue; lethal arrhythmias ... See more keywords