Articles with "lethality precision" as a keyword



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Targeting epigenetics using synthetic lethality in precision medicine

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Published in 2018 at "Cellular and Molecular Life Sciences"

DOI: 10.1007/s00018-018-2866-0

Abstract: Technological breakthroughs in genomics have had a significant impact on clinical therapy for human diseases, allowing us to use patient genetic differences to guide medical care. The “synthetic lethal approach” leverages on cancer-specific genetic rewiring… read more here.

Keywords: medicine; targeting epigenetics; epigenetics using; lethality precision ... See more keywords