Kisspeptin expression features in the arcuate and anteroventral periventricular nuclei of hypothalamus of letrozole-induced polycystic ovarian syndrome in rats
Sign Up to like & getrecommendations! Published in 2017 at "Archives of Gynecology and Obstetrics"
DOI: 10.1007/s00404-017-4509-3
Abstract: PurposePolycystic ovary syndrome (PCOS) is the most common endocrine disorder of the reproductive system characterized by polycystic ovaries and androgen excess. Letrozole is a nonsteroidal aromatase inhibitor that is used in experimental research to induce… read more here.
Keywords: kisspeptin positive; proestrus; control; number ... See more keywords
A comparison of two months pretreatment with GnRH agonists with or without an aromatase inhibitor in women with ultrasound-diagnosed ovarian endometriomas undergoing IVF.
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DOI: 10.1016/j.rbmo.2018.12.028
Abstract: RESEARCH QUESTION Does the addition of an aromatase inhibitor improve IVF outcomes in women with endometriomas when pretreating them with gonadotrophin-releasing hormone agonists? DESIGN Retrospective two-centre cohort study involving 126 women aged 21-39 years who… read more here.
Keywords: aromatase inhibitor; treatment; rate; aromatase ... See more keywords
Prednisone combined with letrozole reduced risk of ovarian hyperstimulation syndrome (OHSS) in women undergoing long-term gonadotropin-releasing hormone analog treatment.
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DOI: 10.21037/apm-21-1699
Abstract: BACKGROUND Ovarian hyperstimulation syndrome (OHSS) is a severe disease that can lead to serious complication. Letrozole has been applied during controlled ovarian hyperstimulation (COH) to reduce the rate of OHSS in women undergoing long-term Gonadotropin-releasing… read more here.
Keywords: prednisone; ovarian hyperstimulation; treatment; group ... See more keywords
In vitro Development of Controlled-Release Nanoniosomes for Improved Delivery and Anticancer Activity of Letrozole for Breast Cancer Treatment
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DOI: 10.2147/ijn.s384085
Abstract: Introduction Breast cancer is among the most prevalent mortal cancers in women worldwide. In the present study, an optimum formulation of letrozole, letrozole-loaded niosome, and empty niosome was developed, and the anticancer effect was assessed… read more here.
Keywords: microscopy; letrozole; breast cancer; release ... See more keywords
Nicotinamide Mononucleotide Alleviates Bile Acid Metabolism and Hormonal Dysregulation in Letrozole-Induced PCOS Mice
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DOI: 10.3390/biology13121028
Abstract: Simple Summary Polycystic ovary syndrome (PCOS) is a complex condition influenced by genetic, metabolic, hormonal, and environmental factors. It often leads to high androgen levels, disrupted ovarian function, and metabolic issues. In this study, we… read more here.
Keywords: mice; nicotinamide mononucleotide; letrozole; androgen levels ... See more keywords
Impact of alcoholic extract from sea cucumber (Holothuria parva) on letrozole–induced polycystic ovary syndrome in adult female rats
Sign Up to like & getrecommendations! Published in 2024 at "Asian Pacific Journal of Reproduction"
DOI: 10.4103/apjr.apjr_3_24
Abstract: To explore the potential therapeutic impact of an alcoholic extract derived from the sea cucumber (Holothuria parva) on letrozole-induced polycystic ovary syndrome (PCOS) in adult female Sprague-Dawley rats. Sixteen female rats, aged 8 to 10… read more here.
Keywords: letrozole; impact alcoholic; cucumber; sea cucumber ... See more keywords
Off-label letrozole for tubal pregnancy monotherapy is not an alternative to methotrexate: a prospective cohort study.
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DOI: 10.5603/gpl.100131
Abstract: OBJECTIVES Inhibition of estradiol production by letrozole may interfere with physiological effects of progesterone necessary to maintain the pregnancy. Treatment of tubal pregnancy (TP) with letrozole would allow to avoid the disadvantages of methotrexate (MTX).… read more here.
Keywords: cohort study; letrozole; tubal pregnancy; pregnancy ... See more keywords