Bifunctional role of leucine 300 of firefly luciferase in structural rigidity.
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DOI: 10.1016/j.ijbiomac.2017.03.069
Abstract: Firefly luciferase is susceptible to thermal inactivation, thereby its intracellular half-life decreased. Previous reports indicated that L300R mutation (LRR mutant) in E354R/Arg356 double mutant (ERR mutant) from Lampyris turkestanicus luciferase has increased its thermal stability… read more here.
Keywords: leucine 300; rigidity; firefly luciferase;