Multi-scale mechanistic modelling of the host defence in invasive aspergillosis reveals leucocyte activation and iron acquisition as drivers of infection outcome
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DOI: 10.1098/rsif.2021.0806
Abstract: Aspergillus species are ubiquitous environmental moulds, with spores inhaled daily by most humans. Immunocompromised hosts can develop an invasive infection resulting in high mortality. There is, therefore, a pressing need for host-centric therapeutics for this… read more here.
Keywords: multi scale; iron acquisition; leucocyte activation; growth ... See more keywords