Articles with "leukaemia stem" as a keyword



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Abemaciclib drives the therapeutic differentiation of acute myeloid leukaemia stem cells

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Published in 2023 at "British Journal of Haematology"

DOI: 10.1111/bjh.18735

Abstract: Self‐renewal and differentiation arrest are two features of leukaemia stem cells (LSCs) responsible for the high relapse rate of acute myeloid leukaemia (AML). To screen drugs to overcome differentiation blockade for AML, we conducted screening… read more here.

Keywords: myeloid; leukaemia stem; abemaciclib; differentiation ... See more keywords