Assessment of Factors Associated With Parental Perceptions of Voluntary Decisions About Child Participation in Leukemia Clinical Trials
Sign Up to like & getrecommendations! Published in 2021 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2021.9038
Abstract: Key Points Question Are health literacy, contextual factors, or sociodemographic characteristics associated with parental perception of voluntariness during informed consent for pediatric leukemia clinical trials? Findings In this cross-sectional study that included 97 parents of… read more here.
Keywords: child participation; clinical trials; leukemia clinical; decisions child ... See more keywords
Vandetanib drives growth arrest and promotes sensitivity to imatinib in chronic myeloid leukemia by targeting ephrin type‐B receptor 4
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Oncology"
DOI: 10.1002/1878-0261.13270
Abstract: The oncogenic role of ephrin type‐B receptor 4 (EPHB4) has been reported in many types of tumors, including chronic myeloid leukemia (CML). Here, we found that CML patients have a higher EPHB4 expression level than… read more here.
Keywords: imatinib; growth; ephrin type; vandetanib ... See more keywords
A Metabolic Reprogramming Amino Acid Polymer as an Immunosurveillance Activator and Leukemia Targeting Drug Carrier for T‐Cell Acute Lymphoblastic Leukemia
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DOI: 10.1002/advs.202104134
Abstract: Abstract Compromised immunosurveillance leads to chemotherapy resistance and disease relapse of hematological malignancies. Amino acid metabolism regulates immune responses and cancer; however, a druggable amino acid metabolite to enhance antitumor immunosurveillance and improve leukemia targeting‐therapy… read more here.
Keywords: immunosurveillance; cell; leukemia; metabolic reprogramming ... See more keywords
Acute Myeloid Leukemia Cells Educate Mesenchymal Stromal Cells toward an Adipogenic Differentiation Propensity with Leukemia Promotion Capabilities
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DOI: 10.1002/advs.202105811
Abstract: Mesenchymal stromal cells (MSCs) are essential elements of the bone marrow (BM) microenvironment, which have been widely implicated in pathways that contribute to leukemia growth and resistance. Recent reports showed genotypic and phenotypic alterations in… read more here.
Keywords: myeloid leukemia; mesenchymal stromal; leukemia; acute myeloid ... See more keywords
DEX-Induced SREBF1 Promotes BMSCs Differentiation into Adipocytes to Attract and Protect Residual T-Cell Acute Lymphoblastic Leukemia Cells After Chemotherapy.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced science"
DOI: 10.1002/advs.202205854
Abstract: T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive malignant blood disorder with a high rate of relapse. Patients relapse as a result of minimal residual disease (MRD), which originates from residual T-ALL cells in the… read more here.
Keywords: cell; leukemia; dex; acute lymphoblastic ... See more keywords
Chronic lymphocytic leukemia in Brazil: A retrospective analysis of 1903 cases
Sign Up to like & getrecommendations! Published in 2017 at "American Journal of Hematology"
DOI: 10.1002/ajh.24779
Abstract: [1] Garcia-Manero G. Myelodysplastic syndromes: 2015 Update on diagnosis, risk-stratification and management. Am J Hematol. 2015;90: 831–841. [2] Arber DA, Orazi A, Hasserjian R, et al. The 2016 revision to the World Health Organization classification… read more here.
Keywords: myelodysplastic syndromes; brazil retrospective; lymphocytic leukemia; leukemia brazil ... See more keywords
Response to Dr. Bain's comment on our review article: Pure Erythroid Leukemia.
Sign Up to like & getrecommendations! Published in 2017 at "American journal of hematology"
DOI: 10.1002/ajh.24862
Abstract: Word Count: N/A Main Text Word Count: 339 Number of References: 3 # Correspondence: Josehp D. Khoury, MD Department of Hematopathology The University of Texas MD Anderson Cancer Center Houston, Texas 77030 Phone: 713-745-2387 Fax:… read more here.
Keywords: aml mrc; article; pel; mds ... See more keywords
Outcome of chronic lymphocytic leukemia patients who switched from either ibrutinib or idelalisib to alternate kinase inhibitor: A retrospective study of the French innovative leukemia organization (FILO)
Sign Up to like & getrecommendations! Published in 2018 at "American Journal of Hematology"
DOI: 10.1002/ajh.24981
Abstract: dose cytarabine for the treatment of older patients with newly diagnosed acute myeloid leukemia. J Clin Oncol. 2012;30(21):2670–2677. [5] Dombret H, Seymour JF, Butrym A, et al. International phase 3 study of azacitidine vs conventional… read more here.
Keywords: older patients; myeloid leukemia; blood; acute myeloid ... See more keywords
Switches of tyrosine‐kinase inhibitors in chronic phase of chronic myeloid leukemia in real life
Sign Up to like & getrecommendations! Published in 2018 at "American Journal of Hematology"
DOI: 10.1002/ajh.25217
Abstract: To the Editor: Imatinib has transformed chronic myeloid leukemia (CML) prognosis with a survival rate of almost 83% at 10 years. The second and third generations of tyrosine-kinase inhibitors (TKIs) have enlarged the therapeutic possibilities.… read more here.
Keywords: first line; group; switch group; leukemia ... See more keywords
Acute myeloid leukemia with minimal differentiation (AML M0) mimicking acute lymphoblastic leukemia
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DOI: 10.1002/ajh.25354
Abstract: A 68-year-old man presented with a history of several months of weakness and weight loss, and was found to be pancytopenic (WBC = 2.02 K/μL, hemoglobin = 8.1 g/dL, hematocrit = 24.4%, platelet count =… read more here.
Keywords: leukemia minimal; myeloid leukemia; lymphoblastic leukemia; acute lymphoblastic ... See more keywords
Obinutuzumab in two patients suffering from immune‐mediated thrombotic thrombocytopenic purpura intolerant to rituximab
Sign Up to like & getrecommendations! Published in 2019 at "American Journal of Hematology"
DOI: 10.1002/ajh.25583
Abstract: lary BCR-ABL1-negative myeloid leukemia in a patient with chronic myeloid leukemia and synchronous cytogenetic abnormalities in Philadelphia-positive and -negative clones during imatinib therapy. Leukemia. 2007;21(11):2394-2396. 5. Krysiak K, Christopher MJ, Skidmore ZL, et al. A… read more here.
Keywords: obinutuzumab two; myeloid leukemia; chronic myeloid; philadelphia chromosome ... See more keywords