Anti-leukemia effect associated with down-regulated CD47 and up-regulated calreticulin by stimulated macrophages in co-culture
Sign Up to like & getrecommendations! Published in 2020 at "Cancer Immunology, Immunotherapy"
DOI: 10.1007/s00262-020-02728-z
Abstract: CD47 is over-expressed in Acute Myeloid Leukemia (AML) and functions as an inhibitory signal, suppressing phagocytosis by binding to signal regulatory protein α (SIRPα) on the surface of macrophages. Inhibition of CD47 restores the immune… read more here.
Keywords: leukemia effect; cd47; anti leukemia; aml ... See more keywords
Chemodiversity and Anti-Leukemia Effect of Metabolites from Penicillium setosum CMLD 18
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DOI: 10.3390/metabo13010023
Abstract: Penicillium setosum represents a Penicillium species recently described, with little up-to-date information about its metabolic and biological potential. Due to this scenario, we performed chemical and biological studies of P. setosum CMLD18, a strain isolated… read more here.
Keywords: chemodiversity anti; leukemia effect; anti leukemia; penicillium setosum ... See more keywords