Articles with "leukemia mll1" as a keyword



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The development of inhibitors targeting the Mixed lineage leukemia 1 (MLL1)-WD repeat domain 5 protein (WDR5) Protein-Protein Interaction.

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Published in 2019 at "Current medicinal chemistry"

DOI: 10.2174/0929867326666190528080514

Abstract: Mixed lineage leukemia 1 (MLL1), an important member of histone methyltransferases (HMT) family, is closely associated with human acute leukemia. MLL1 could specially catalyze mono-, di-, and trimethylation of histone 3 lysine 4 (H3K4) via… read more here.

Keywords: protein; leukemia mll1; mll1; interaction ... See more keywords