The impacts of zanubrutinib on immune cells in patients with chronic lymphocytic leukemia/small lymphocytic lymphoma
Sign Up to like & getrecommendations! Published in 2019 at "Hematological Oncology"
DOI: 10.1002/hon.2667
Abstract: Ibrutinib, a first‐generation Bruton's tyrosine kinase (BTK) inhibitor, could improve immunity of relapsed or refractory (R/R) chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) patients. Whether zanubrutinib, a second‐generation selective BTK inhibitor, has similar effects as ibrutinib… read more here.
Keywords: cll; lymphocytic leukemia; treatment; small lymphocytic ... See more keywords
Blood and Guts: Diarrhea from Colonic Involvement in Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma
Sign Up to like & getrecommendations! Published in 2018 at "Digestive Diseases and Sciences"
DOI: 10.1007/s10620-018-5264-4
Abstract: An 81-year-old male was initially evaluated in a local emergency department for a 6-week history of diarrhea. He had a history of coronary artery disease with remote coronary artery bypass graft and mechanical mitral valve… read more here.
Keywords: lymphocytic leukemia; small lymphocytic; blood; chronic lymphocytic ... See more keywords
Concurrent cutaneous localization of Langerhans cell sarcoma and chronic lymphocytic leukemia/small lymphocytic lymphoma in a patient with a history of chronic lymphocytic leukemia/small lymphocytic lymphoma
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cutaneous Pathology"
DOI: 10.1111/cup.13571
Abstract: The phenomenon of histiocytic/dendritic cell sarcomas arising through transformation of a pre‐existed lymphoproliferative disease is called transdifferentiation. Langerhans cell sarcoma transdifferentiating from chronic lymphocytic leukemia/small lymphocytic lymphoma is extremely rare and all the reported cases… read more here.
Keywords: lymphocytic leukemia; small lymphocytic; chronic lymphocytic; leukemia small ... See more keywords
Presentation of Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma in a Warthin Tumor: Case Report and Literature Review
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Surgical Pathology"
DOI: 10.1177/1066896917734371
Abstract: Warthin tumor is the second most common salivary gland neoplasm. It occurs more commonly in males than in females. Malignant transformation in Warthin tumor is a rare but well-recognized phenomenon; however, the development or presentation… read more here.
Keywords: lymphoma; lymphocytic leukemia; warthin tumor; chronic lymphocytic ... See more keywords
MAJIC: a phase III trial of acalabrutinib + venetoclax versus venetoclax + obinutuzumab in previously untreated chronic lymphocytic leukemia or small lymphocytic lymphoma.
Sign Up to like & getrecommendations! Published in 2022 at "Future oncology"
DOI: 10.2217/fon-2022-0456
Abstract: Here we describe the rationale and design of MAJIC, a phase III, prospective, multicenter, randomized trial comparing the combination of the BTK inhibitor acalabrutinib plus the BCL2 inhibitor venetoclax versus the combination of venetoclax plus… read more here.
Keywords: lymphocytic leukemia; leukemia small; venetoclax; small lymphocytic ... See more keywords
Survival adjusting for crossover: phase 3 study of ibrutinib vs. chlorambucil in older patients with untreated chronic lymphocytic leukemia/small lymphocytic lymphoma
Sign Up to like & getrecommendations! Published in 2018 at "Haematologica"
DOI: 10.3324/haematol.2017.175380
Abstract: Ibrutinib, a first-in-class, once-daily inhibitor of Bruton’s tyrosine kinase, is indicated by the US FDA for the treatment of patients with chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) and allows for treatment without chemotherapy. This broad… read more here.
Keywords: ibrutinib; lymphocytic leukemia; small lymphocytic; chronic lymphocytic ... See more keywords
NCCN Guidelines® Insights: Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma, Version 3.2022.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the National Comprehensive Cancer Network : JNCCN"
DOI: 10.6004/jnccn.2022.0031
Abstract: The treatment landscape of chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) has significantly evolved in recent years. Targeted therapy with Bruton's tyrosine kinase (BTK) inhibitors and BCL-2 inhibitors has emerged as an effective chemotherapy-free option for… read more here.
Keywords: lymphocytic leukemia; chronic lymphocytic; nccn guidelines; leukemia small ... See more keywords