A Novel Chromosomal Aberration in the Pathogenesis of Transient Leukemia of Down Syndrome
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DOI: 10.1007/s12098-021-03699-4
Abstract: To the Editor: The index case was a term girl with a smooth perinatal transition with Down phenotypic features. Examination revealed hepatosplenomegaly (liver span-7 cm and spleen 2 cm below the left costal margin). Blood… read more here.
Keywords: q31 q21; transient leukemia; pathogenesis; leukemia syndrome ... See more keywords
Post-induction MRD by FCM and GATA1-PCR are significant prognostic factors for myeloid leukemia of Down syndrome
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DOI: 10.1038/s41375-021-01157-w
Abstract: Myeloid leukemia of Down syndrome (ML-DS) is associated with good response to chemotherapy, resulting in favorable outcomes. However, no universal prognostic factors have been identified to date. To clarify a subgroup with high risk of… read more here.
Keywords: mrd; gata1; prognostic factors; myeloid leukemia ... See more keywords