Leukemogenic Functions of Mutant ASXL1 Are Regulated By CDK-Mediated Phosphorylation
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DOI: 10.1182/blood-2019-125959
Abstract: Additional sex combs-like 1 (ASXL1) is recurrently mutated in various myeloid neoplasms and its mutations confer poor prognosis. Most of the ASXL1 mutations in myeloid malignancies are frameshift or nonsense mutations, leading to expression of… read more here.
Keywords: asxl1; cdk mediated; leukemogenic functions; phosphorylation ... See more keywords