Global methylation of blood leukocyte DNA and risk of melanoma
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DOI: 10.1002/ijc.30577
Abstract: Global DNA methylation, possibly influenced by lifestyle and environmental factors, has been suggested to play an active role in carcinogenesis. However, its role in melanoma has rarely been explored. The aims of this study were… read more here.
Keywords: melanoma; leukocyte dna; methylation; risk ... See more keywords
Streptozotocin-induced leukocyte DNA damage in rats
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DOI: 10.1080/01480545.2018.1510956
Abstract: Abstract Although several studies using peripheral blood samples suggest that DNA damage is caused by streptozotocin (STZ) per se, our hypothesis is that DNA damage is caused by STZ-induced glycemic changes. Thus, we aimed at… read more here.
Keywords: dna damage; leukocyte dna; stz; damage ... See more keywords
Metabolic fitness in relation to genetic variation and leukocyte DNA methylation.
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DOI: 10.1152/physiolgenomics.00077.2018
Abstract: Metabolic syndrome (MetS) is a highly prevalent condition causing increased risk of several life-threatening diseases. MetS has a pronounced hereditary basis but is also influenced by environmental factors, partly through epigenetic mechanisms. In this study,… read more here.
Keywords: leukocyte dna; methylation; variation leukocyte; genetic variants ... See more keywords