Chemoattractant-mediated leukocyte trafficking enables HIV dissemination from the genital mucosa.
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DOI: 10.1172/jci.insight.88533
Abstract: HIV vaginal transmission accounts for the majority of newly acquired heterosexual infections. However, the mechanism by which HIV spreads from the initial site of viral entry at the mucosal surface of the female genital tract… read more here.
Keywords: dissemination genital; infection; leukocyte trafficking; mucosa ... See more keywords
β2-Integrins – Regulatory and Executive Bridges in the Signaling Network Controlling Leukocyte Trafficking and Migration
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DOI: 10.3389/fimmu.2022.809590
Abstract: Leukocyte trafficking is an essential process of immunity, occurring as leukocytes travel within the bloodstream and as leukocyte migration within tissues. While it is now established that leukocytes can utilize the mesenchymal migration mode or… read more here.
Keywords: leukocyte trafficking; migration; migration mode; integrins regulatory ... See more keywords
Loss of CD11b Accelerates Lupus Nephritis in Lyn-Deficient Mice Without Disrupting Glomerular Leukocyte Trafficking
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DOI: 10.3389/fimmu.2022.875359
Abstract: Systemic lupus erythematosus (SLE) is a complex, heterogeneous autoimmune disease. A common manifestation, lupus nephritis, arises from immune complex deposition in the kidney microvasculature promoting leukocyte activation and infiltration, which triggers glomerular damage and renal… read more here.
Keywords: loss; cd11b; leukocyte trafficking; lupus nephritis ... See more keywords