Levetiracetam-induced rhabdomyolysis: the first Italian case
Sign Up to like & getrecommendations! Published in 2018 at "Neurological Sciences"
DOI: 10.1007/s10072-018-3421-3
Abstract: To the Editor, Levetiracetam (LEV) is an antiepileptic drug with widespread use for the treatment of both focal and generalized seizures. Until recently, it was generally deemed to be one of the safest antiepileptic drugs,… read more here.
Keywords: muscle; first italian; case; rhabdomyolysis ... See more keywords
Population pharmacokinetics and dose-response relationship of levetiracetam in adult patients with epilepsy
Sign Up to like & getrecommendations! Published in 2017 at "Epilepsy Research"
DOI: 10.1016/j.eplepsyres.2017.02.011
Abstract: Levetiracetam (LEV) is commonly used as a mono- or adjunctive therapy for treating patients with partial and generalized epilepsy. This study aimed to develop a population pharmacokinetic (PK) model of LEV, based on sparse data,… read more here.
Keywords: dose response; pharmacokinetics dose; population pharmacokinetics; lev ... See more keywords
Mode of seizure inhibition by sodium channel blockers, an SV2A ligand, and an AMPA receptor antagonist in a rat amygdala kindling model
Sign Up to like & getrecommendations! Published in 2019 at "Epilepsy Research"
DOI: 10.1016/j.eplepsyres.2019.03.011
Abstract: PURPOSE A number of antiepileptic drugs (AEDs) with a variety of modes of action, are effective in treating focal seizures. Several AEDs, such as perampanel (PER), levetiracetam (LEV), lacosamide (LCM), lamotrigine (LTG), and carbamazepine (CBZ),… read more here.
Keywords: stimulation; ltg cbz; lev; lcm ltg ... See more keywords
Binding interaction of isoxsuprine hydrochloride and levothyroxine to milk β-lactoglobulin; from the perspective of comparison.
Sign Up to like & getrecommendations! Published in 2018 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2017.12.117
Abstract: Isoxsuprine hydrochloride (ISO) and levothyroxine (LEV) are medicines which can be utilized alone or simultaneously by pregnant women. The purpose of this work is to investigate the separate and simultaneous interaction of ISO and LEV… read more here.
Keywords: iso; isoxsuprine hydrochloride; levothyroxine; lev ... See more keywords
The leading-edge vortex of yacht sails
Sign Up to like & getrecommendations! Published in 2018 at "Ocean Engineering"
DOI: 10.1016/j.oceaneng.2018.02.029
Abstract: Abstract It has been suggested that a stable Leading Edge Vortex (LEV) can be formed from the sharp leading edge of asymmetric spinnakers, which are high-lift sails used by yachts to sail downwind. If the… read more here.
Keywords: leading edge; edge; sail; edge vortex ... See more keywords
A scaling for vortex formation on swept and unswept pitching wings
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Fluid Mechanics"
DOI: 10.1017/jfm.2017.710
Abstract: We examine the dynamics of the leading-edge vortex (LEV) on a rapidly pitching plate with the aim of elucidating the underlying flow physics that dictates the stability and circulation of the LEV. A wide variety… read more here.
Keywords: vortex formation; vortex; scaling vortex; formation swept ... See more keywords
Structural Evolution of Ag-LEV Zeolite upon Heating: An In Situ Single-Crystal X-ray Diffraction (SC-XRD) and X-ray Absorption Spectroscopy (XAS) Study
Sign Up to like & getrecommendations! Published in 2020 at "ACS Omega"
DOI: 10.1021/acsomega.0c04455
Abstract: Ag-exchanged zeolites are known to have improved sorption and catalytic properties compared to the raw natural material. The application range of Ag-exchanged zeolites is linked to the stability of the exchanged form and its structural… read more here.
Keywords: single crystal; structural evolution; lev; spectroscopy ... See more keywords
PSIV-8 Effect of Feeding Levucell SB® 10 Titan Advantage and YANG on Performance, Blood Parameters, and Fecal VFA of Nursery Pigs
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Animal Science"
DOI: 10.1093/jas/skab054.300
Abstract: A total of 496 weaned pigs (19 ± 1 d of age) were used in a 3-phase feeding program to evaluate effects of Levucell SB 10 Titan Advantage, a live yeast, Saccharomyces cerevisiae boulardii (LEV;… read more here.
Keywords: blood; lev; nursery pigs; fecal vfa ... See more keywords
Serum levetiracetam concentrations after transdermal levetiracetam administration, 3 times daily, to healthy cats
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Veterinary Internal Medicine"
DOI: 10.1111/jvim.15412
Abstract: Background Repeated oral administration of antiepileptic drugs can be challenging for cat owners, resulting in reduced compliance, poor seizure control, and reduced quality of life for cats. Levetiracetam (LEV) has several properties that make it… read more here.
Keywords: administration; transdermal lev; serum concentrations; lev ... See more keywords
Caffeine impairs anticonvulsant effects of levetiracetam in the maximal electroshock seizure threshold test in mice
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Basic and Clinical Physiology and Pharmacology"
DOI: 10.1515/jbcpp-2022-0224
Abstract: Abstract Objectives Caffeine is the most widely used psychoactive substance in the world. Animal studies indicate that acute caffeine exposure at high doses may induce seizures and diminish the anticonvulsant activity of antiepileptic drugs (AEDs)… read more here.
Keywords: seizure threshold; lev; caffeine; electroshock seizure ... See more keywords
Blockade of TASK-1 Channel Improves the Efficacy of Levetiracetam in Chronically Epileptic Rats
Sign Up to like & getrecommendations! Published in 2022 at "Biomedicines"
DOI: 10.3390/biomedicines10040787
Abstract: Tandem of P domains in a weak inwardly rectifying K+ channel (TWIK)-related acid sensitive K+-1 channel (TASK-1) is an outwardly rectifying K+ channel that acts in response to extracellular pH. TASK-1 is upregulated in the… read more here.
Keywords: epileptic rats; blockade task; lev; non responders ... See more keywords