Early in vitro development of daptomycin non-susceptibility in high-level aminoglycoside-resistant Enterococcus faecalis predicts the efficacy of the combination of high-dose daptomycin plus ampicillin in an in vivo model of experimental endocarditis
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Antimicrobial Chemotherapy"
DOI: 10.1093/jac/dkx016
Abstract: Background Previous studies showed development of daptomycin non-susceptibility (DNS: MIC >4 mg/L) in Enterococcus faecalis infections. However, no studies have assessed the efficacy of the combination of daptomycin/ampicillin against E. faecalis strains developing DNS in the… read more here.
Keywords: high level; faecalis; daptomycin ampicillin; aminoglycoside resistant ... See more keywords
Prevalence of high-level aminoglycoside resistance and genes encoding aminoglycoside-modifying enzymes in Enterococcus faecalis and Enterococcus faecium isolated in a university hospital in Tokyo.
Sign Up to like & getrecommendations! Published in 2020 at "Japanese journal of infectious diseases"
DOI: 10.7883/yoken.jjid.2019.416
Abstract: High-level aminoglycoside resistance (HLAR) limits treatment options for invasive enterococcal infections. We examined the prevalence of HLAR by disk diffusion method, carriage of genes for aminoglycoside-modifying enzymes by PCR, and production of β-lactamase by nitrocefin-based… read more here.
Keywords: high level; faecium; aminoglycoside resistance; level aminoglycoside ... See more keywords