Abstract B04: High-level expression of oncogenic KRAS is required to transform LKB1 mutant tissue in vivo
Sign Up to like & getrecommendations! Published in 2020 at "Molecular Cancer Research"
DOI: 10.1158/1557-3125.ras18-b04
Abstract: Although activating mutations in the GTPase KRAS are oncogenic and implicated in various malignancies, mutations in KRAS alone are inefficient to transform epithelia. In lung adenocarcinoma, KRAS mutations occur at high frequency and co-segregate with… read more here.
Keywords: oncogenic kras; level expression; tissue; lkb1 ... See more keywords
Low-level expression of necroptosis factors indicates a poor prognosis of the squamous cell carcinoma subtype of non-small-cell lung cancer.
Sign Up to like & getrecommendations! Published in 2021 at "Translational lung cancer research"
DOI: 10.21037/tlcr-20-1027
Abstract: Background The programmed cell death pathway necroptosis may synergize with the DNA damage response (DDR) in opposing tumor progression. While our basic mechanistic understanding of the necroptotic cell death advances rapidly, its prognostic implications have… read more here.
Keywords: necroptosis; expression; level expression; cell ... See more keywords
Low-Level Expression of CD138 Marks Naturally Arising Anergic B Cells
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DOI: 10.4110/in.2022.22.e50
Abstract: Autoreactive B cells are not entirely deleted, but some remain as immunocompetent or anergic B cells. Although the persistence of autoreactive B cells as anergic cells has been shown in transgenic mouse models with the… read more here.
Keywords: anergic cells; level expression; expression; low level ... See more keywords