A comprehensive comparison of residue-level methylation levels with the regression-based gene-level methylation estimations by ReGear
Sign Up to like & getrecommendations! Published in 2021 at "Briefings in bioinformatics"
DOI: 10.1093/bib/bbaa253
Abstract: MOTIVATION DNA methylation is a biological process impacting the gene functions without changing the underlying DNA sequence. The DNA methylation machinery usually attaches methyl groups to some specific cytosine residues, which modify the chromatin architectures.… read more here.
Keywords: gene level; methylation; level methylation; gene ... See more keywords
Abstract 3493: Read-level methylation pattern extraction for high-multiplex large-scale targeted NGS assay
Sign Up to like & getrecommendations! Published in 2024 at "Cancer Research"
DOI: 10.1158/1538-7445.am2024-3493
Abstract: The abnormal changes in DNA methylation are linked to the early stages of carcinogenesis. Identifying these epigenetic changes in circulating tumor DNA (ctDNA) can reveal potential biomarkers for the early diagnosis of various cancers. However,… read more here.
Keywords: level methylation; methylation; high multiplex; multiplex large ... See more keywords