A3216 Relationship between genetic variants of ACE2 gene and circulating levels of ACE2 and its metabolites
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Hypertension"
DOI: 10.1097/01.hjh.0000547992.85595.35
Abstract: Objectives: Because heritability had remarkable effects on circulating ACE2, we designed this study to shed light on whether circulating levels of ACE2, angiotensin- (1- 7) and angiotensin- (1- 9) were linked to single nucleotide polymorphisms… read more here.
Keywords: levels ace2; angiotensin levels; circulating angiotensin; ace2 gene ... See more keywords
Effect of ACE1 polymorphism rs1799752 on protein levels of ACE2, the SARS-CoV-2 entry receptor, in alveolar lung epithelium
Sign Up to like & getrecommendations! Published in 2021 at "ERJ Open Research"
DOI: 10.1183/23120541.00940-2020
Abstract: Coronavirus disease 19 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is currently invoking a pandemic with a huge medical and financial impact. One of the striking features of this pandemic is the… read more here.
Keywords: levels ace2; epithelium; rs1799752; protein levels ... See more keywords
ACE2 Serum Levels as Predictor of Infectability and Outcome in COVID-19
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.836516
Abstract: Background COVID‐19 can generate a broad spectrum of severity and symptoms. Many studies analysed the determinants of severity but not among some types of symptoms. More importantly, very few studies analysed patients highly exposed to… read more here.
Keywords: levels ace2; serum levels; highly exposed; covid ... See more keywords
Oral Lisinopril Raises Tissue Levels of ACE2, the SARS-CoV-2 Receptor, in Healthy Male and Female Mice
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.798349
Abstract: Angiotensin-converting enzyme 2 (ACE2) is the established cellular receptor for SARS-CoV-2. However, it is unclear whether ACE1 inhibitors (e.g., lisinopril) or angiotensin receptor blockers (e.g., losartan) alter tissue ACE2 expression. This study sought to determine… read more here.
Keywords: levels ace2; lisinopril; sars cov; receptor ... See more keywords