CXCL13 as a Biomarker of Complex Common Variable Immunodeficiency
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Clinical Immunology"
DOI: 10.1007/s10875-025-01963-2
Abstract: Common Variable Immunodeficiency (CVID) is a group of heterogeneous disorders with common denominators of impaired antibody production and function, and recurrent infections. Currently, prognostic biomarkers for CVID are limited. CXCL13 is a critical regulator of… read more here.
Keywords: common variable; cxcl13; levels cxcl13; variable immunodeficiency ... See more keywords
High serum levels of CXCL13 predict lower response to csDMARDs in both ACPA-positive and ACPA-negative early rheumatoid arthritis.
Sign Up to like & getrecommendations! Published in 2024 at "Rheumatology"
DOI: 10.1093/rheumatology/keae596
Abstract: OBJECTIVES Increased circulating levels of CXCL13 reflect synovial production and indicate immune dysregulation in patients with rheumatoid arthritis (RA). Here we tested whether CXCL13 predicts response to first-line treatment with methotrexate (MTX) in patients with… read more here.
Keywords: response; acpa negative; levels cxcl13; acpa positive ... See more keywords