Aqua-soluble DDQ reduces the levels of Drp1 and A&bgr; and inhibits abnormal interactions between A&bgr; and Drp1 and protects Alzheimer’s disease neurons from A&bgr;- and Drp1-induced mitochondrial and synaptic toxicities
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DOI: 10.1093/hmg/ddx226
Abstract: The purpose of our study was to develop a therapeutic target that can reduce Aβ and Drp1 levels, and also can inhibit abnormal interactions between Aβ and Drp1 in AD neurons. To achieve this objective,… read more here.
Keywords: ddq; bgr drp1; ddq treated; levels drp1 ... See more keywords