High levels of urinary complement proteins are associated with chronic renal damage and proximal tubule dysfunction in immunoglobulin A nephropathy
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DOI: 10.1111/nep.13477
Abstract: Complement activation is involved in the pathogenesis and progression of immunoglobulin A nephropathy (IgAN); however, the clinical implication of abnormal complement protein levels in serum and urine is not clear. To address this we analyzed… read more here.
Keywords: immunoglobulin nephropathy; high levels; complement; complement proteins ... See more keywords
Elevated Levels of Urinary Extracellular Vesicle Fibroblast-Specific Protein 1 in Patients with Active Crescentic Glomerulonephritis
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DOI: 10.1159/000495217
Abstract: Background/Aims: Extracellular vesicles (EVs), including exosomes, are present in various bodily fluids, including urine. We and others previously reported that cells expressing fibroblast-specific protein 1 (FSP1) accumulate within damaged glomeruli, and that urinary FSP1, as… read more here.
Keywords: fibroblast specific; specific protein; soluble cd163; levels urinary ... See more keywords