Articles with "leveraging allelic" as a keyword



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MARS: leveraging allelic heterogeneity to increase power of association testing

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Published in 2021 at "Genome Biology"

DOI: 10.1186/s13059-021-02353-8

Abstract: In standard genome-wide association studies (GWAS), the standard association test is underpowered to detect associations between loci with multiple causal variants with small effect sizes. We propose a statistical method, Model-based Association test Reflecting causal… read more here.

Keywords: allelic heterogeneity; mars leveraging; leveraging allelic; power ... See more keywords