Abstract PR18: Leveraging synthetic lethality to target convergent therapeutic resistance
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Cancer Therapeutics"
DOI: 10.1158/1538-8514.synthleth-pr18
Abstract: Our laboratory uses genomic and pharmacological methods to define the pathways of resistance to targeted anticancer therapies. Toward this end, we recently developed a technique in which engineered lentiviral cDNAs encoding activators of major oncogenic… read more here.
Keywords: synthetic lethality; lethality target; resistance; leveraging synthetic ... See more keywords