Effect of Levetiracetam on Cognition in Patients With Alzheimer Disease With and Without Epileptiform Activity: A Randomized Clinical Trial.
Sign Up to like & getrecommendations! Published in 2021 at "JAMA neurology"
DOI: 10.1001/jamaneurol.2021.3310
Abstract: Importance Network hyperexcitability may contribute to cognitive dysfunction in patients with Alzheimer disease (AD). Objective To determine the ability of the antiseizure drug levetiracetam to improve cognition in persons with AD. Design, Setting, and Participants… read more here.
Keywords: trial; alzheimer disease; levetiracetam; epileptiform activity ... See more keywords
Oral levetiracetam for prevention of busulfan-induced seizures in adult hematopoietic cell transplant
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Clinical Pharmacy"
DOI: 10.1007/s11096-020-00977-7
Abstract: Background Antiseizure prophylaxis is recommended when high-dose of busulfan is given as part of the conditioning regimens in the allogenic hematopoietic stem cell transplant. Phenytoin has been widely used but its pharmacokinetics and pharmacodynamics profile… read more here.
Keywords: busulfan; oral levetiracetam; levetiracetam; prevention busulfan ... See more keywords
Randomized Controlled Trial Evaluating Levetiracetam as First-line Therapy for Seizures in Neonates
Sign Up to like & getrecommendations! Published in 2020 at "Indian Pediatrics"
DOI: 10.1007/s13312-020-1965-9
Abstract: This multicenter, randomized, blinded, controlled, trial investigated the efficacy and safety of levetiracetam compared with phenobarbital as a preferred treatment for neonatal seizures of any cause. The primary outcome variable was complete seizure freedom for… read more here.
Keywords: randomized controlled; randomly assigned; levetiracetam; controlled trial ... See more keywords
Nose-to-brain delivery of levetiracetam after intranasal administration to mice.
Sign Up to like & getrecommendations! Published in 2019 at "International journal of pharmaceutics"
DOI: 10.1016/j.ijpharm.2019.04.047
Abstract: Despite being one of the most commonly prescribed antiepileptic drugs, levetiracetam is marketed in oral and intravenous dosage forms, which are associated to drug-drug interactions and drug-resistant epilepsy (DRE). The purpose of the present study… read more here.
Keywords: intranasal; levetiracetam; drug; intranasal administration ... See more keywords
A Case of Possible Levetiracetam Induced Aseptic Meningitis vs Viral Meningitis
Sign Up to like & getrecommendations! Published in 2022 at "CNS Spectrums"
DOI: 10.1017/s1092852922000281
Abstract: Abstract Introduction Meningitis causes inflammation of the meninges and when bacteria are not the cause may be considered aseptic. Drug-induced aseptic meningitis (DIAM) can arise from the use of certain medications. The pathophysiology of DIAM… read more here.
Keywords: induced aseptic; viral meningitis; meningitis; levetiracetam ... See more keywords
Drug–drug interaction between levetiracetam and non-vitamin K antagonist anticoagulants
Sign Up to like & getrecommendations! Published in 2019 at "European Heart Journal"
DOI: 10.1093/eurheartj/ehy780
Abstract: In the updated guide on NOAC use in patients with non-valvular atrial fibrillation, the European Heart Rhythm Association recommends against the use of the antiepileptic drug, levetiracetam, due to potential P-glycoprotein-mediated drug–drug interaction (DDI). While… read more here.
Keywords: digoxin; drug interaction; levetiracetam; drug ... See more keywords
884: PHARMACOKINETIC AND PHARMACODYNAMIC EVALUATION OF LEVETIRACETAM IN CRITICALLY ILL PATIENTS WITH SAH
Sign Up to like & getrecommendations! Published in 2020 at "Critical Care Medicine"
DOI: 10.1097/01.ccm.0000631672.09389.23
Abstract: Introduction/Hypothesis: Levetiracetam is frequently utilized as seizure prophylaxis due to its favorable side effect profile compared to other antiepileptic drugs. Levetiracetam is renally eliminated through glomerular filtration and exhibits linear pharmacokinetics. A recent pharmacokinetic study… read more here.
Keywords: pharmacokinetic pharmacodynamic; pharmacodynamic evaluation; day; clearance ... See more keywords
Effects of atorvastatin and aspirin on post-stroke epilepsy and usage of levetiracetam
Sign Up to like & getrecommendations! Published in 2020 at "Medicine"
DOI: 10.1097/md.0000000000023577
Abstract: Abstract Objective: Atorvastatin and aspirin have been used in treating different forms of epilepsy. However, their effect on post-stroke epilepsy (PSE) still needs to be validated by large-scale clinical studies. In addition, their impact on… read more here.
Keywords: stroke epilepsy; pse; atorvastatin aspirin; levetiracetam ... See more keywords
Psychotic Symptoms Related to the Prophylactic Use of Levetiracetam After Brain Surgery.
Sign Up to like & getrecommendations! Published in 2019 at "American Journal of Therapeutics"
DOI: 10.1097/mjt.0000000000000940
Abstract: To the Editor: Levetiracetam is a new antiepileptic that is effective as an adjunctive therapy for refractory partial-onset seizures, primary generalized tonic–clonic seizures, myoclonic seizures of juvenile myoclonic epilepsy,1 and the seizure prophylaxis after brain… read more here.
Keywords: patient; levetiracetam; brain surgery; psychotic symptoms ... See more keywords
Carbamazepine versus levetiracetam in epilepsy due to neurocysticercosis
Sign Up to like & getrecommendations! Published in 2020 at "Acta Neurologica Scandinavica"
DOI: 10.1111/ane.13355
Abstract: The choice of antiepileptic drug (AED) in newly diagnosed neurocysticercosis (NCC) patients with epilepsy continues to be arbitrary. We compared efficacy and side effect profile of levetiracetam (LEV) and carbamazepine (CBZ) for the treatment of… read more here.
Keywords: levetiracetam epilepsy; versus levetiracetam; neurocysticercosis; levetiracetam ... See more keywords
Personalized prediction model for seizure‐free epilepsy with levetiracetam therapy: a retrospective data analysis using support vector machine
Sign Up to like & getrecommendations! Published in 2018 at "British Journal of Clinical Pharmacology"
DOI: 10.1111/bcp.13720
Abstract: To predict the probability of a seizure‐free (SF) state in patients with epilepsy (PWEs) after treatment with levetiracetam and to identify the clinical and electroencephalographic (EEG) factors that affect outcomes. read more here.
Keywords: model seizure; levetiracetam; seizure free; prediction model ... See more keywords