Percutaneous Transesophageal Gastro‐Tubing as an Alternative Procedure of Levodopa Administration in Parkinson's Disease
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DOI: 10.1002/mdc3.13014
Abstract: Most patients with Parkinson’s disease (PD) experience a wearing-off phenomenon in advanced stages of the disease requiring frequent oral administrations of levodopa. In addition, more than 80% of patients with PD develop dysphagia, which is… read more here.
Keywords: percutaneous transesophageal; administration; levodopa; transesophageal gastro ... See more keywords
Gastrointestinal Motility and Response to Levodopa in Parkinson's Disease: A Proof‐of‐Concept Study
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DOI: 10.1002/mds.29176
Abstract: Simultaneous measurement of gastrointestinal transit time (GITT) and plasma levodopa concentration (PLC) is crucial to understanding the effect of dysfunctional motility on levodopa response in patients with Parkinson's disease (PwPD). read more here.
Keywords: parkinson disease; motility response; gastrointestinal motility; levodopa ... See more keywords
Sensor-based algorithmic dosing suggestions for oral administration of levodopa/carbidopa microtablets for Parkinson’s disease: a first experience
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DOI: 10.1007/s00415-019-09183-6
Abstract: ObjectiveDosing schedules for oral levodopa in advanced stages of Parkinson’s disease (PD) require careful tailoring to fit the needs of each patient. This study proposes a dosing algorithm for oral administration of levodopa and evaluates… read more here.
Keywords: dosing suggestions; levodopa; sensor based; parkinson disease ... See more keywords
Levodopa/carbidopa intestinal gel for pain related to levodopa-induced motor complications in Parkinson’s disease
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DOI: 10.1007/s10072-022-06043-6
Abstract: Dear Editor, Pain is a rather frequent and highly disabling non-motor symptom of Parkinson’s disease (PD). In advanced PD patients, pain frequently occurs or is aggravated by the “off” condition and may benefit by dopamine… read more here.
Keywords: involuntary movements; therapy; dose; score ... See more keywords
A Web Resource for Levodopa-Induced Dyskinesia Genetics in Parkinson’s Disease
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DOI: 10.1007/s12021-017-9327-z
Abstract: Levodopa-induced dyskinesia (LID) is a side effect of Parkinson’s disease (PD) therapy. The time span from levodopa therapy initiation to the appearance of LID is variable between patients and several publications have investigated a potential… read more here.
Keywords: levodopa; genetics; levodopa induced; web resource ... See more keywords
Levodopa-induced skin disorders in patients with Parkinson disease: a systematic literature review approach
Sign Up to like & getrecommendations! Published in 2019 at "Acta Neurologica Belgica"
DOI: 10.1007/s13760-019-01195-3
Abstract: The use of levodopa for treatment of Parkinson’s disease is a well-established clinical practice. Data about the true incidence and severity of cutaneous complications associated with the use of levodopa are largely lacking. Aim of… read more here.
Keywords: skin disorders; levodopa; review; malignant melanoma ... See more keywords
Pharmacokinetics of Rytary®, An Extended-Release Capsule Formulation of Carbidopa–Levodopa
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DOI: 10.1007/s40262-017-0511-y
Abstract: Parkinson’s disease (PD) is a chronic progressive neurological disorder characterized by resting tremor, rigidity, bradykinesia, gait disturbance, and postural instability. Levodopa, the precursor to dopamine, coadministered with carbidopa or benserazide, aromatic amino acid decarboxylase inhibitors,… read more here.
Keywords: release; carbidopa levodopa; capsule formulation; levodopa ... See more keywords
Levodopa facilitates improvements in gait kinetics at the hip, not the ankle, in individuals with Parkinson's disease.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of biomechanics"
DOI: 10.1016/j.jbiomech.2021.110366
Abstract: Parkinson's disease symptoms impair gait, limit mobility, and reduce independence. Levodopa improves muscle activation, strength, and coordination; thus, facilitating increased step length, but few studies have evaluated the underlying forces associated with medication-induced gait improvements.… read more here.
Keywords: levodopa; hip; gait kinetics; disease ... See more keywords
Estimulación cerebral profunda en pacientes parkinsonianos con intolerancia a levodopa
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DOI: 10.1016/j.neucir.2017.09.005
Abstract: Resumen La estimulacion cerebral profunda (ECP) es un tratamiento eficaz para pacientes con enfermedad de Parkinson con complicaciones motoras. El elemento mas importante que predice la respuesta a la ECP es la respuesta a la… read more here.
Keywords: cerebral profunda; levodopa; con; pacientes parkinsonianos ... See more keywords
Simultaneous electrochemical determination of levodopa and piroxicam using a glassy carbon electrode modified with a ZnO–Pd/CNT nanocomposite
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DOI: 10.1039/c8ra03460e
Abstract: A highly conductive electrochemical sensor was constructed for the simultaneous electrochemical determination of levodopa and piroxicam by modification of a glassy carbon electrode with a ZnO–Pd/CNT nanocomposite (GCE/ZnO–Pd/CNTs). The ZnO–Pd/CNT nanocomposite was synthesized by the… read more here.
Keywords: determination levodopa; zno; levodopa piroxicam; levodopa ... See more keywords
Doxycycline to treat levodopa-induced dyskinesias in Parkinson's disease: a preliminary study
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DOI: 10.1055/s-0043-1768668
Abstract: Abstract Background Levodopa-induced dyskinesia (LID) is a common motor complication of levodopa therapy in patients with Parkinson's disease (PD). Doxycycline is a widely used and inexpensive tetracycline with anti-inflammatory properties. Objective To evaluate the efficacy… read more here.
Keywords: parkinson disease; doxycycline; levodopa; week ... See more keywords