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   Articles with "levodopa challenge" as a keyword



Levodopa challenge test: indications, protocol, and guide

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recommendations! Published in 2020 at "Journal of Neurology"

DOI: 10.1007/s00415-020-09810-7

Abstract: A drug challenge test in Parkinson’s disease, such as the levodopa challenge test (LCT), is an easy and generally safe procedure, which has been used by clinicians for various indications. The results of the test… read more here.

Keywords: challenge; indications protocol; levodopa challenge; test indications ... See more keywords

Remote levodopa challenge test in Parkinson's disease: Feasibility, reliability, validity and economic value

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recommendations! Published in 2024 at "European Journal of Neurology"

DOI: 10.1111/ene.16423

Abstract: The aim was to demonstrate the feasibility, reliability and validity of an in‐home remote levodopa challenge test (LCT), as delivered through an online platform, for patients with Parkinson's disease (PwPD). read more here.

Keywords: levodopa challenge; feasibility reliability; reliability validity; parkinson disease ... See more keywords

The role of gut microbiota tyrosine decarboxylases in levodopa pharmacokinetics: insights from a levodopa challenge test

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recommendations! Published in 2025 at "BMC Neurology"

DOI: 10.1186/s12883-025-04428-6

Abstract: The gut microbiota is known to influence levodopa metabolism in the intestinal tract, primarily through the action of tyrosine decarboxylase, an enzyme encoded by the tyrosine decarboxylase gene (tyrDC). However, the effect of the abundance… read more here.

Keywords: gut microbiota; levodopa challenge; levodopa pharmacokinetics; levodopa ... See more keywords

Can Levodopa Challenge Testing Predict the Effect of Deep Brain Stimulation? One-Year Outcomes in a Chinese Cohort

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recommendations! Published in 2021 at "Frontiers in Aging Neuroscience"

DOI: 10.3389/fnagi.2021.764308

Abstract: Objective: Our study examined whether levodopa challenge test (LCT) results could predict quality of life (QoL) outcomes after surgery to implant subthalamic nucleus deep brain stimulation (STN-DBS) electrodes to treat advanced Parkinson’s disease (PD). Methods:… read more here.

Keywords: iii tremor; updrs iii; levodopa challenge;