Articles with "levomepromazine clozapine" as a keyword



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Levomepromazine and clozapine induce the main human cytochrome P450 drug metabolizing enzyme CYP3A4

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Published in 2020 at "Pharmacological Reports"

DOI: 10.1007/s43440-020-00157-4

Abstract: Background Cytochrome P450 (CYP) enzymes are involved in the metabolism of many important endogenous substrates (steroids, melatonin), drugs and toxic xenobiotics. Their induction accelerates drug metabolism and elimination. The present study aimed at examining the… read more here.

Keywords: clozapine induce; clozapine; cyp3a4; levomepromazine clozapine ... See more keywords