Preclinical safety evaluation of levonadifloxacin, a novel anti‐methicillin‐resistant Staphyloccocus aureus benzoquinolizine fluoroquinolone by intravenous and oral administration
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DOI: 10.1002/jat.4300
Abstract: Fluoroquinolone (FQ) antibacterials have drawn heightened attention from various international regulatory agencies due to their class‐specific side effects. Levonadifloxacin is a novel broad spectrum benzoquinolizine FQ active against methicillin‐resistant Staphyloccocus aureus (MRSA). Owing to FQ‐associated… read more here.
Keywords: toxicology; safety; preclinical safety; wck 771 ... See more keywords
Meeting the Unmet Need in the Management of MDR Gram-Positive Infections with Oral Bactericidal Agent Levonadifloxacin
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DOI: 10.1155/2022/2668199
Abstract: Levonadifloxacin (intravenous) and its oral prodrug alalevonadifloxacin are broad-spectrum antibacterial agents developed for the treatment of difficult-to-treat infections caused by multidrug-resistant Gram-positive bacteria, especially methicillin-resistant Staphylococcus aureus, atypical bacteria, anaerobic bacteria, and biodefence pathogens as… read more here.
Keywords: gram; meeting unmet; need management; unmet need ... See more keywords