Investigating the Influence of Excipients on the Stability of Levothyroxine Sodium Pentahydrate.
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DOI: 10.1021/acs.molpharmaceut.1c00217
Abstract: A range of tablet excipients were evaluated for their influence on the physical form and chemical stability of levothyroxine sodium pentahydrate (LSP; C15H10I4NNaO4ยท5H2O). LSP-excipient binary powder blends were stored under two conditions: (a) in hermetically… read more here.
Keywords: stability levothyroxine; sodium pentahydrate; sodium; stability ... See more keywords
Effect of Levothyroxine Sodium Tablets on Pregnancy Outcome and Offspring Development Quotient of SCH during Pregnancy
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DOI: 10.1155/2022/9001881
Abstract: Objective To investigate the effect of levothyroxine sodium tablets (L-T4) on pregnancy outcome and offspring development quotient in patients with subclinical hypothyroidism (SCH) during pregnancy. Material and Methods. Pregnant women with gestational age less than… read more here.
Keywords: development; treatment; pregnancy; sodium tablets ... See more keywords
New Insights on Solid-State Changes in the Levothyroxine Sodium Pentahydrate during Dehydration and its Relationship to Chemical Instability
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DOI: 10.1208/s12249-018-1264-0
Abstract: Levothyroxine sodium pentahydrate (LEVO) tablets have been on the US market since the mid-twentieth century and remain the most highly prescribed product. Unfortunately, levothyroxine sodium tablets have also been one of the most highly recalled… read more here.
Keywords: solid state; chemical instability; sodium pentahydrate; sodium ... See more keywords
Preparation and in vitro evaluation of injectable formulations of levothyroxine sodium using in situ forming hydrogel temperature-responsive systems based on PLA-PEG-PLA and PLGA-PEG-PLGA triblock copolymers
Sign Up to like & getrecommendations! Published in 2022 at "Iranian Journal of Basic Medical Sciences"
DOI: 10.22038/ijbms.2022.62576.13842
Abstract: Objective(s): Recently, great attention has been paid to developing new drug delivery systems to manage the rate, time, and site of drug release. We aimed to design a novel drug delivery system to support targeted… read more here.
Keywords: levothyroxine sodium; peg pla; pla peg; plga ... See more keywords