Targeting epithelial expressed Sialyl Lewis glycans improves colonic mucosal wound healing and protects against colitis.
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DOI: 10.1172/jci.insight.135843
Abstract: Dysregulated healing of injured mucosa is a hallmark of many pathological conditions including inflammatory bowel disease. Mucosal injury and chronic inflammation including persistent neutrophil (PMN) infiltration are also associated with alterations in epithelial glycosylation. Previous… read more here.
Keywords: wound healing; sialyl lewis; lewis glycans; mucosal ... See more keywords