Biodistribution and pharmacokinetic profiles of an altered peptide ligand derived from heat-shock proteins 60 in Lewis rats
Sign Up to like & getrecommendations! Published in 2019 at "Cell Stress and Chaperones"
DOI: 10.1007/s12192-019-01054-3
Abstract: Human heat-shock protein 60 (HSP60) is an autoantigen involved in the pathogenesis of rheumatoid arthritis (RA). Epitopes derived from HSP60 can trigger activation of regulatory T cells (Treg). CIGB-814 is an altered peptide ligand (APL)… read more here.
Keywords: lewis rats; peptide ligand; heat shock; altered peptide ... See more keywords
P95. Immunmodulatory effects of intrathecal administration of triamcinolone in experimental autoimmune neuritis model in lewis rats
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DOI: 10.1016/j.clinph.2018.04.717
Abstract: Objective We studied the immunmodulatory effects of triamcinolone applied intrathecally in the animal model of experimental autoimmune neuritis (EAN) in Lewis rats. Background Therapeutic efficacy of intravenous corticosteroids in chronic autoimmune neuritis has been shown… read more here.
Keywords: model; lewis rats; triamcinolone; autoimmune neuritis ... See more keywords
The effect of high-fat diet and 13-cis retinoic acid application on lipid profile, glycemic response and oxidative stress in female Lewis rats
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DOI: 10.1371/journal.pone.0238600
Abstract: Vitamin A and its metabolites are key regulators of the development of adipose tissue and associated metabolic complications. The aim of this study was to determine the effect of high fat diet and 13-cis retinoic… read more here.
Keywords: high fat; fat diet; effect high; lewis rats ... See more keywords