Synthesis of daunorubicin conjugates with fragments of H type 5, Lea, Lex antigens and N-fucoglycan
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DOI: 10.1007/s11172-019-2708-8
Abstract: Daunorubicin was conjugated with spacered N-glycosides of di- and trisaccharides containing terminal α-l-fucopyranose residues. The synthesis was carried out by N-monoalkylation of daunorubicin hydrochloride (1) in aqueous DMF in the presence of NaHCO3 using N-β-glycoside… read more here.
Keywords: fragments type; lea lex; lex antigens; type lea ... See more keywords