Inhibition of the transcriptional repressor LexA: Withstanding drug resistance by inhibiting the bacterial mechanisms of adaptation to antimicrobials.
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DOI: 10.1016/j.lfs.2019.117116
Abstract: AIMS LexA protein is a transcriptional repressor which regulates the expression of more than 60 genes belonging to the SOS global regulatory network activated by damages to bacterial DNA. Considering its role in bacteria, LexA… read more here.
Keywords: transcriptional repressor; inhibition; lexa self; resistance ... See more keywords