An Introduction to LFA-1/ICAM-1 Interactions in T-Cell Motility.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-9036-8_1
Abstract: The inherent ability of T-cells to migrate is critical for a fully functional immune system, both in normal immune surveillance and for mounting an adaptive immune response. At the same time, inappropriate trafficking of T-cells… read more here.
Keywords: cell motility; icam interactions; introduction lfa; lfa icam ... See more keywords
The magnitude of LFA-1/ICAM-1 forces fine-tune TCR-triggered T cell activation
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DOI: 10.1126/sciadv.abg4485
Abstract: T cells defend against cancer and viral infections by rapidly scanning the surface of target cells seeking specific peptide antigens. This key process in adaptive immunity is sparked upon T cell receptor (TCR) binding of… read more here.
Keywords: tune; lfa icam; tcr; cell ... See more keywords
LFA-1/ ICAM-1 promotes NK cell cytotoxicity associated with the pathogenesis of ocular toxoplasmosis in murine model
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DOI: 10.1371/journal.pntd.0010848
Abstract: Ocular toxoplasmosis (OT) is one of the most common causes of posterior uveitis. However, the pathogenic mechanisms of OT have not been well elucidated. Here, we used C57BL/6 (B6) mice to establish OT by peroral… read more here.
Keywords: murine model; lfa icam;
Distinct Roles of LFA-1 and ICAM-1 on ILC2s Control Lung Infiltration, Effector Functions, and Development of Airway Hyperreactivity
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DOI: 10.3389/fimmu.2020.542818
Abstract: Asthma is a heterogeneous airway inflammatory disease characterized by increased airway hyperreactivity (AHR) to specific and unspecific stimuli. Group 2 innate lymphoid cells (ILC2)s are type-2 cytokine secreting cells capable of inducing eosinophilic lung inflammation… read more here.
Keywords: ilc2s; lfa icam; airway hyperreactivity; effector functions ... See more keywords