Trans-synaptic LGI1–ADAM22–MAGUK in AMPA and NMDA receptor regulation
Sign Up to like & getrecommendations! Published in 2021 at "Neuropharmacology"
DOI: 10.1016/j.neuropharm.2021.108628
Abstract: Exquisitely-regulated synaptic transmission and plasticity underlie higher brain functions such as learning and memory. PSD-95, a member of the MAGUK family, scaffolds an array of postsynaptic proteins including AMPA and NMDA receptors, and plays essential… read more here.
Keywords: receptor; ampa nmda; lgi1 adam22; trans synaptic ... See more keywords
Structural basis of epilepsy-related ligand–receptor complex LGI1–ADAM22
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DOI: 10.1038/s41467-018-03947-w
Abstract: Epilepsy is a common brain disorder throughout history. Epilepsy-related ligand–receptor complex, LGI1–ADAM22, regulates synaptic transmission and has emerged as a determinant of brain excitability, as their mutations and acquired LGI1 autoantibodies cause epileptic disorders in… read more here.
Keywords: receptor; lgi1; epilepsy related; lgi1 adam22 ... See more keywords