In Vivo Injection of Anti-LGI1 Antibodies into the Rodent M1 Cortex and Hippocampus Is Ineffective in Inducing Seizures
Sign Up to like & getrecommendations! Published in 2023 at "eNeuro"
DOI: 10.1523/eneuro.0267-22.2023
Abstract: Abstract Autoimmune encephalitis (AIE) associated with antibodies directed against the leucine-rich glioma inactivated 1 (LGI1) protein is the second most common AIE and is responsible for deleterious neocortical and limbic epileptic seizures. Previous studies demonstrated… read more here.
Keywords: injection; anti lgi1; lgi1 antibodies; vivo injection ... See more keywords
Phenotypic Spectrum of CASPR2 and LGI1 Antibodies Associated Neurological Disorders in Children
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pediatrics"
DOI: 10.3389/fped.2022.815976
Abstract: Objectives The clinical data of patients with double-positive for leucine-rich glioma-inactivated protein 1 (LGI1) and contactin-associated protein-like 2 (CASPR2) antibodies is limited, particularly for children. This study aimed to investigate and summarize the clinical features… read more here.
Keywords: lgi1 antibodies; caspr2 lgi1; ivig ivmp; caspr2 ... See more keywords