Structure of an LGR dimer, an evolutionary predecessor of glycoprotein hormone receptors.
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DOI: 10.1038/s41467-025-66676-x
Abstract: Glycoprotein hormones (GpHs) produced in the human pituitary act through receptors (GpHRs) in the gonads to support reproduction and in the thyroid for metabolism. GpHs are heterodimeric cystine-knot proteins; their receptors bind cognate hormones at… read more here.
Keywords: hormone; structure lgr; glycoprotein; lgr dimer ... See more keywords