Anatomically and Functionally Distinct Lung Mesenchymal Populations Marked by Lgr5 and Lgr6
Sign Up to like & getrecommendations! Published in 2017 at "Cell"
DOI: 10.1016/j.cell.2017.07.028
Abstract: Summary The diversity of mesenchymal cell types in the lung that influence epithelial homeostasis and regeneration is poorly defined. We used genetic lineage tracing, single-cell RNA sequencing, and organoid culture approaches to show that Lgr5… read more here.
Keywords: anatomically functionally; functionally distinct; lgr5 lgr6; lgr6 ... See more keywords
The Maresin 1-LGR6 axis decreases respiratory syncytial virus-induced lung inflammation.
Sign Up to like & getrecommendations! Published in 2023 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2206480120
Abstract: The resolution of infection is an active process with specific molecular and cellular mechanisms that temper inflammation and enhance pathogen clearance. Here, the specialized pro-resolving mediator (SPM) Maresin 1 (MaR1) inhibited respiratory syncytial virus (RSV)-induced inflammation.… read more here.
Keywords: inflammation; syncytial virus; maresin; lgr6 ... See more keywords
LGR6 Acts as an Oncogene and Induces Proliferation and Migration of Gastric Cancer Cells.
Sign Up to like & getrecommendations! Published in 2022 at "Critical reviews in eukaryotic gene expression"
DOI: 10.1615/critreveukaryotgeneexpr.2021041271
Abstract: Leucine rich repeat containing G protein-coupled receptor 6 (LGR6) belongs to the G protein-coupled receptor family, and it exhibits up-regulated expression in various types of human cancer. However, there are few reports of LGR6 contributing… read more here.
Keywords: cell; proliferation migration; expression; lgr6 ... See more keywords