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Data-Driven Analyses of Longitudinal Hippocampal Imaging Trajectories: Discrimination and Biomarker Prediction of Change Classes

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Published in 2022 at "Journal of Alzheimer's Disease"

DOI: 10.3233/jad-215289

Abstract: Background: Hippocampal atrophy is a well-known biomarker of neurodegeneration, such as that observed in Alzheimer’s disease (AD). Although distributions of hippocampal volume trajectories for asymptomatic individuals often reveal substantial heterogeneity, it is unclear whether interpretable… read more here.

Keywords: biomarkers risk; biomarker; driven analyses; risk factors ... See more keywords