The LHX2-OTX2 transcriptional regulatory module controls retinal pigmented epithelium differentiation and underlies genetic risk for age-related macular degeneration
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DOI: 10.1371/journal.pbio.3001924
Abstract: Tissue-specific transcription factors (TFs) control the transcriptome through an association with noncoding regulatory regions (cistromes). Identifying the combination of TFs that dictate specific cell fate, their specific cistromes and examining their involvement in complex human… read more here.
Keywords: retinal pigmented; pigmented epithelium; lhx2; risk ... See more keywords