Estimation of familial recurrence risk of malignancy: Application of liability threshold model in genetic counseling
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DOI: 10.1111/cge.14171
Abstract: Apart from some Mendelianâinherited tumors, malignancies are multifactorial diseases, and reported data are often the only sources to estimate familial recurrence risk. Edwards' approximation formula has provided one way forward, but it uses estimates only… read more here.
Keywords: recurrence risk; liability threshold; threshold model; risk ... See more keywords