Explore the effects of Huang‐Lian‐Jie‐Du‐Tang on Alzheimer's disease by UPLC‐QTOF/MS‐based plasma metabolomics study
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Pharmaceutical and Biomedical Analysis"
DOI: 10.1016/j.jpba.2017.12.053
Abstract: Graphical abstract Figure. No caption available. HighlightsThe underlying mechanism of HLJDT was explored by valid UPLC–MS‐based metabolomics.Memory amelioration and reduced neuroinflammation were observed in HLJDT group mice.Callback of lipid metabolic disorder indicates the effects of… read more here.
Keywords: huang lian; metabolism; alzheimer disease; lian jie ... See more keywords
Explore of the beneficial effects of Huang-Lian-Jie-Du Decoction on diabetic encephalopathy in db/db mice by UPLC-Q-Orbitrap HRMS/MS based untargeted metabolomics analysis.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of pharmaceutical and biomedical analysis"
DOI: 10.1016/j.jpba.2020.113652
Abstract: Diabetic encephalopathy (DE) is a severe diabetic complication with cognitive dysfunction. Huang-Lian-Jie-Du Decoction (HLJDD), a famous traditional Chinese formula, is effective for the treatment of diabetes mellitus and Alzheimer's disease in clinical practices, however, the… read more here.
Keywords: diabetic encephalopathy; huang lian; analysis; lian jie ... See more keywords
A Preliminary Inquiry Into the Potential Mechanism of Huang-Lian-Jie-Du Decoction in Treating Rheumatoid Arthritis via Network Pharmacology and Molecular Docking
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2021.740266
Abstract: Huang-Lian-Jie-Du decoction (HLJDD) has been widely applied to treat inflammation-associated diseases for thousands of years in China. However, the concrete molecular mechanism of HLJDD in the treatment of rheumatoid arthritis (RA) remains unclear. In this… read more here.
Keywords: molecular docking; network; pharmacology; huang lian ... See more keywords