Articles with "library" as a keyword



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Selection of an artificial paraquat-specific binding protein from a ribosome display library based on a lipocalin scaffold.

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Published in 2020 at "Biotechnology and applied biochemistry"

DOI: 10.1002/bab.2059

Abstract: In this study, an anticalin that could specifically bind paraquat (PQ), a quaternary nitrogen herbicide, as a new set of engineered receptor protein with antibody-like properties was generated to detect PQ concentration. To this end,… read more here.

Keywords: library; selection artificial; ribosome display; binding protein ... See more keywords

Sequence‐based design and construction of synthetic nanobody library

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Published in 2024 at "Biotechnology and Bioengineering"

DOI: 10.1002/bit.28707

Abstract: Nanobody (Nb), the smallest antibody fragments known to bind antigens, is now widely applied to various studies, including protein structure analysis, bioassay, diagnosis, and biomedicine. The traditional approach to generating specific nanobodies involves animal immunization… read more here.

Keywords: library; library library; nanobody; based design ... See more keywords

Construction of A Digital Fetus Library for Radiation Dosimetry.

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Published in 2022 at "Medical physics"

DOI: 10.1002/mp.15905

Abstract: PURPOSE Accurate estimation of fetal absorbed dose and radiation risks are crucial for radiation protection and important for radiological imaging research owing to the high radio-sensitivity of the fetus. Computational anthropomorphic models have been widely… read more here.

Keywords: radiation dosimetry; library; dosimetry; radiation ... See more keywords

A prostate cancer tissue specific spectral library for targeted proteomic analysis.

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Published in 2021 at "Proteomics"

DOI: 10.1002/pmic.202100147

Abstract: Prostate cancer is the most common cancer in male worldwide. Mass spectrometry-based targeted proteomics has demonstrated great potential in quantifying proteins from formalin-fixed paraffin-embedded (FFPE) and (fresh) frozen biopsy tissues. Here we provide a comprehensive… read more here.

Keywords: prostate; library; analysis; prostate cancer ... See more keywords
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Systematic Chemogenetic Library Assembly.

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Published in 2020 at "Cell chemical biology"

DOI: 10.1016/j.chembiol.2020.07.004

Abstract: Chemogenetic libraries, collections of well-defined chemical probes, provide tremendous value to biomedical research but require substantial effort to ensure diversity as well as quality of the contents. We have assembled a chemogenetic library by data… read more here.

Keywords: library; library assembly; chemogenetic library; systematic chemogenetic ... See more keywords

An 8-(Diazomethyl) Quinoline Derivatized Acyl-CoA in Silico Mass Spectral Library Reveals the Landscape of Acyl-CoA in Aging Mouse Organs.

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Published in 2024 at "Analytical chemistry"

DOI: 10.1021/acs.analchem.4c02113

Abstract: Acyl-Coenzyme As (acyl-CoAs) are essential intermediates to incorporate carboxylic acids into the bioactive metabolic network across all species, which play important roles in lipid remodeling, fatty acids, and xenobiotic carboxylic metabolism. However, due to the… read more here.

Keywords: coa; library; acyl coas; acyl coa ... See more keywords

Multi-Reference Spectral Library Yields Almost Complete Coverage of Heterogeneous LC-MS/MS Data Sets.

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Published in 2019 at "Journal of proteome research"

DOI: 10.1021/acs.jproteome.8b00819

Abstract: Spectral libraries play a central role in the analysis of data-independent-acquisition (DIA) proteomics experiments. A main assumption in current spectral library tools is that a single characteristic intensity pattern (CIP) suffices to describe the fragmentation… read more here.

Keywords: data sets; library; almost complete; coverage heterogeneous ... See more keywords

Facile Preparation of a Glycopolymer Library by PET-RAFT Polymerization for Screening the Polymer Structures of GM1 Mimics

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Published in 2022 at "ACS Omega"

DOI: 10.1021/acsomega.2c00719

Abstract: Commercialized oligosaccharides such as GM1 are useful for biological applications but generally expensive. Thus, facile access to an effective alternative is desired. Glycopolymers displaying both carbohydrate and hydrophobic units are promising materials as alternatives to… read more here.

Keywords: preparation glycopolymer; library; glycopolymer library; facile preparation ... See more keywords

Programmable Synthetic Upstream Activating Sequence Library for Fine-Tuning Gene Expression Levels in Saccharomyces cerevisiae.

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Published in 2022 at "ACS synthetic biology"

DOI: 10.1021/acssynbio.1c00511

Abstract: A wide dynamic range of promoters is necessary for fine-tuning transcription levels. However, weak intensity and narrow dynamic range limit transcriptional regulation via constitutive promoters. The upstream activation sequence (UAS) located upstream of the core… read more here.

Keywords: uas library; library; sequence; fine tuning ... See more keywords

Positioning the Academic Library within the Institution: Structures and Challenges

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Published in 2018 at "New Review of Academic Librarianship"

DOI: 10.1080/13614533.2019.1582078

Abstract: Higher education institutions are experiencing significant change within an ever increasingly complex political and economic environment. Universities are now more accountable than ever before as they try to operate in a highly competitive global market… read more here.

Keywords: within institution; library; academic library; library within ... See more keywords

Decentering Whiteness in the Academic Library: Investigating the Impact of Institutional Whiteness on Organizational Culture through a Case Study of a Grassroots Anti-Racist Community of Practice in an Academic Library

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Published in 2024 at "New Review of Academic Librarianship"

DOI: 10.1080/13614533.2024.2328158

Abstract: Abstract This article reports on a small-scale research project conducted in the summer of 2021. It explores the impact of a grass-roots Anti-Racist Community of Practice on organizational culture and how much it influenced the… read more here.

Keywords: library; practice; culture; anti racist ... See more keywords