Articles with "library ligation" as a keyword



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An in-library ligation strategy and its application in CRISPR/Cas9 screening of high-order gRNA combinations

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Published in 2022 at "Nucleic Acids Research"

DOI: 10.1093/nar/gkac458

Abstract: Abstract Simultaneous targeting multiple genes is a big advantage of CRISPR (clustered regularly interspaced short palindromic repeats) genome editing but challenging to achieve in CRISPR screening. The crosstalk among genes or gene products is a… read more here.

Keywords: high order; library ligation; crispr; ligation strategy ... See more keywords