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Published in 2022 at "Cancer Medicine"
DOI: 10.1002/cam4.5243
Abstract: Choriocarcinoma is a rare and aggressive gynecological malignancy. The standard treatment is systemic chemotherapy as choriocarcinoma exhibits high chemosensitivity. However, refractory choriocarcinoma exhibits chemoresistance; thus, the prognosis remains very poor. This study aimed to identify…
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Keywords:
choriocarcinoma;
drug library;
novel therapeutic;
library screening ... See more keywords
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Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-9220-1_1
Abstract: The existence of tightly integrated cross talk through multiple signaling and effector pathways has been appreciated in malignant cells. The realization of the plasticity of such networks is stimulating the development of combinational therapy to…
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Keywords:
sirna library;
negative breast;
identify complementary;
library screening ... See more keywords
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Published in 2020 at "Cellular and Molecular Gastroenterology and Hepatology"
DOI: 10.1016/j.jcmgh.2020.05.002
Abstract: Background & Aims Esophageal adenocarcinoma (EAC) develops from within Barrett’s esophagus (BE) concomitant with gastroesophageal reflux disease (GERD). Wound healing processes and cellular transitions, such as epithelial–mesenchymal transitions, may contribute to the development of BE…
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Keywords:
high grade;
library screening;
content imaging;
cellular transitions ... See more keywords
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Published in 2018 at "PLoS ONE"
DOI: 10.1371/journal.pone.0201270
Abstract: Yeast two-hybrid (Y2H) is a well-established genetics-based system that uses yeast to selectively display binary protein-protein interactions (PPIs). To meet the current need to unravel complex PPI networks, several adaptations have been made to establish…
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Keywords:
library screening;
two hybrid;
method;
yeast two ... See more keywords