Re-evaluation of the 18 non-human protein standards used to create the Empirical Statistical Model for Decoy Library Searching.
Sign Up to like & getrecommendations! Published in 2020 at "Analytical biochemistry"
DOI: 10.1016/j.ab.2020.113680
Abstract: The Empirical Statistical Model (ESM) for decoy library searching fused the expected amino acid sequence of 18 non-human protein standards to a human decoy library. The ESM assumed a priori the standards were pure such… read more here.
Keywords: protein; empirical statistical; non human; statistical model ... See more keywords
Sensitive and Specific Spectral Library Searching with CompOmics Spectral Library Searching Tool and Percolator.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of proteome research"
DOI: 10.1021/acs.jproteome.2c00075
Abstract: Maintaining high sensitivity while limiting false positives is a key challenge in peptide identification from mass spectrometry data. Here, we investigate the effects of integrating the machine learning-based postprocessor Percolator into our spectral library searching… read more here.
Keywords: spectral library; percolator; compomics spectral; searching tool ... See more keywords