Multiphoton microscopy assessment of the structure and variability changes of dermal connective tissue in vulvar lichen sclerosus: A pilot study
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Biophotonics"
DOI: 10.1002/jbio.202200036
Abstract: In this article, we offer a novel classification of progressive changes in the connective tissue of dermis in vulvar lichen sclerosus (VLS) relying on quantitative assessment of the second harmonic generation (SHG) signal received from… read more here.
Keywords: microscopy; vulvar lichen; connective tissue; lichen sclerosus ... See more keywords
Differentiating Morphea from Lichen Sclerosus by Using Multiphoton Microscopy Combined with U-Net Model for Elastic Fiber Segmentation.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of biophotonics"
DOI: 10.1002/jbio.202300078
Abstract: This paper describes a methodology to differentiate morphea from lichen sclerosus based on examination with multiphoton microscopy (MPM) composed of two-photon excited fluorescence (TPEF) and second harmonic generation (SHG). Subcellular-resolution images were acquired by MPM… read more here.
Keywords: lichen sclerosus; morphea lichen; fiber; microscopy ... See more keywords
Current treatment of lichen sclerosus and stricture
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DOI: 10.1007/s00345-019-03030-z
Abstract: Lichen sclerosus (LS) is a common cause of urethral stricture disease. The purpose of this article is to review the literature over the past 5 years, to describe current treatment of lichen sclerosus as it… read more here.
Keywords: treatment; lichen sclerosus; stricture; current treatment ... See more keywords
Genital lichen sclerosus in childhood and adolescence—a retrospective case series of 15 patients: early diagnosis is crucial to avoid long-term sequelae
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DOI: 10.1007/s00431-017-3004-y
Abstract: AbstractLichen sclerosus is a chronic skin disease, mainly localised at the introitus and perineum. When the condition remains untreated, gradual atrophy of skin structures leads to permanent scarring, making early diagnosis and treatment crucial. We… read more here.
Keywords: sclerosus; treatment; skin; early diagnosis ... See more keywords
Lichen sclerosus presenting as an isolated bulbar urethral stricture
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DOI: 10.1016/j.eucr.2021.101794
Abstract: Lichen sclerosus (LS) is a chronic inflammatory condition of the anogenital skin that can cause significant urinary and sexual dysfunction in men, particularly by means of destructive urethral disease. LS is traditionally thought to progress… read more here.
Keywords: sclerosus presenting; isolated bulbar; urethral stricture; lichen sclerosus ... See more keywords
The long-term clinical consequences of Juvenile Vulvar Lichen Sclerosus, a systematic review.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of the American Academy of Dermatology"
DOI: 10.1016/j.jaad.2019.08.030
Abstract: BACKGROUND Vulvar lichen sclerosus (VLS) occurring in juveniles (children and adolescents) may have repercussions throughout life. OBJECTIVE We sought to assess the evidence available on the long-term consequences of juvenile vulvar lichen sclerosus (JVLS). METHODS… read more here.
Keywords: lichen sclerosus; long term; vulvar lichen; term ... See more keywords
Vulvar basal cell carcinoma in a patient with long-standing lichen sclerosus
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DOI: 10.1016/j.jdcr.2018.07.012
Abstract: BCC: basal cell carcinoma LS: lichen sclerosus SCC: squamous cell carcinoma INTRODUCTION Lichen sclerosus (LS) is a chronic, inflammatory dermatosis most commonly affecting the vulva. It is estimated that LS is associated with up to… read more here.
Keywords: lichen sclerosus; cell carcinoma; cell; basal cell ... See more keywords
Extragenital lichen sclerosus et atrophicus within a skin graft scar
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DOI: 10.1016/j.jdcr.2018.09.007
Abstract: Lichen sclerosus et atrophicus (LSA) is rare chronic relapsing skin condition typically arising in postmenopausal women and prepubescent children in the genital area. Only 6% of cases occur in extragenital skin without concomitant anogenital involvement.1… read more here.
Keywords: lichen sclerosus; skin; sclerosus atrophicus;
Gene silencing of extracellular matrix protein 1 (ECM1) results in phenotypic alterations of dermal fibroblasts reminiscent of clinical features of lichen sclerosus.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of dermatological science"
DOI: 10.1016/j.jdermsci.2020.06.010
Abstract: BACKGROUND Lichen sclerosus (LS) is an acquired inflammatory mucocutaneous disease affecting the anogenital area, characterized histologically by hyalinosis and thickened vessel walls in the dermis. The presence of serum autoantibodies against extracellular matrix protein 1… read more here.
Keywords: matrix protein; extracellular matrix; matrix; lichen sclerosus ... See more keywords
Does HPV infection have impact on results of photodynamic treatment of vulvar lichen sclerosus?
Sign Up to like & getrecommendations! Published in 2020 at "Photodiagnosis and photodynamic therapy"
DOI: 10.1016/j.pdpdt.2020.102138
Abstract: BACKGROUND The association between lichen sclerosus (LS) and human papilloma virus (HPV) infections remains unclear. The co-occurrence of both pathologies possibly affecting the effectiveness of treatment and prognosis is also uncertain. This study aimed to… read more here.
Keywords: lichen sclerosus; treatment; results photodynamic; hpv infection ... See more keywords
Staged Urethroplasty for Penile Urethral Strictures From Lichen Sclerosus and Failed Hypospadias Repair.
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DOI: 10.1016/j.urology.2017.10.020
Abstract: OBJECTIVE To present our technique for staged urethroplasty with buccal mucosa graft. METHODS The patient presented is a 42-year-old man with a history of congenital hypospadias repaired as a child. He developed a penile urethral… read more here.
Keywords: staged urethroplasty; sclerosus failed; failed hypospadias; hypospadias repair ... See more keywords